Associate Director / Scientific Manager, Gnotobiotic Vivarium Head
The complex ecosystem of bacteria that comprise our gut microbiome are inextricably tied to the overall quality of human health. Comet Medicine is a new start-up company poised to leverage the power of active microbial communities to address high unmet medical needs. Our approach lies at the intersection of microbiology, chemistry, and genomics and uniquely enables us to harness the power of the microbiome and define the potential of this new therapeutic modality.
Comet was founded by two leading academics in the microbiome field (Stanford Professors Michael Fischbach and Dylan Dodd) as well as Venrock, one of the oldest venture capital funds in the United States.
Reporting to the VP of Research, the gnotobiotic vivarium head, is responsible for creating and maintaining all aspects of a world-class breach-free vivarium facility. Key tasks include the following:
- Build a new gnotobiotic facility – including ordering, designing SOPs, testing and QCing sterility, maintaining the highest level of sterility requirements
- Build team – starting with one gnotobiotic technician, with potential to grow the team more after 18 months
- Maintain a gnotobiotic mouse facility. Responsibilities include mouse husbandry; breeding; maintaining cages; record keeping; cleaning of equipment and facility; ordering supplies; building, modifying, and sterilizing gnotobiotic isolators and other supplies
- Collaborate with researchers to maintain controlled experiments to ensure high quality biologically results
- Assist scientific team in planning and performing experiments with the gnotobiotic mice. This includes but not limited to oral inoculation and sample collection and preparation
- Maintaining a breach-free gnotobiotic vivarium and a colony to support all experimental needs for the company
- Critical thinking skills and clear communication are a necessity to provide strategic experimental guidance and contribute to data interpretation with the team
- A strong ability to flex with the changing needs of a nimble fast paced research organization
- Work independently and as a member of a team to rapidly assess vivarium issues, questions, or breaches and take appropriate action with minimal guidance
Candidate must have a minimum of a BS in biology. Microbiology degree, and a LAT or LATG certification preferred. Candidate should have experience running a gnotobiotic facility.
Candidate will need to demonstrate aptitudes in foresight, planning and ability to organize and schedule the many tasks associated with running a gnotobiotic mouse facility. Candidate should be flexible, excited to wear the many hats to meet the dynamic needs of a startup environment, proactive and positive. This person should also have a desire to contribute to a vibrant and dynamic culture.
Some ability to build and assemble equipment is desired. Understanding the principals of sterilization is a key facet of the position. Must have ability to lift 50 lbs and stand for extended periods of time.Personal Profile
The Gnotobiotic Vivarium Head will be a dynamic and innovative scientist with a well-developed sense of teamwork. He or she will have the interpersonal skills required to communicate and collaborate effectively with a first-rate scientific team as well as manage a small vivarium team, playing a critical role in the development of novel microbiome therapeutics to support the development of exciting new therapies across a variety of diseases.